Gastric ulcers that occur on the inside of the stomach 2. The most common causes of refractory ulcers … Both types are referred to as peptic ulcers. Your digestive tract is coated with a mucous layer that normally protects against acid. Title: Peptic Ulcer Disease: 1 Peptic Ulcer Disease. Definition: Peptic ulcer is a hole or open sore in the lining of the stomach, duodenum (beginning of the small intestine) or oesophagus. Chronic peptic ulcer (stomach) is a mucosal defect which penetrates the muscularis mucosae and muscularis propria, produced by acid-pepsin aggression. A circumscribed ulceration of the gastrointestinal mucosa occurring in areas exposed to acid and pepsin and most often caused by Helicobacter pylori infection. Etiology. She looked for a PCP’s advice as she had a tarry stool in the early morning which she had never experienced before. • Duodenal ulcers are four times as common as gastric ulcers and occur mainly in the duodenal cap. The acid can create a painful open sore that may bleed. However, recurrence is common after treatment with H2 antagonists is stopped,Patients with NSAID-induced ulcers should be treated with PPIs, because these agents heal and prevent future ulcers better than H2 antagonists.Acute stress ulcers: These drugs are useful in managing acute … PEPTIC ULCER Risk factors include 2,4: 1. – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 419ae3-OGI0O Chronic peptic ulcer it is caused by high chlorhydro-peptic gastric secretion, as a result of either parietal cell hyperplasia, excessive secretory response (i.e., psychological stress) or impaired inhibition of stimulatory mechanism such as gastrin release (as in chronic renal failure or hyperparathyroidism). Aims: The primary cause of peptic ulcer disease (approx. The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. 5. -… Log in Upload File. Free + Easy to edit + Professional + Lots backgrounds. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Download Peptic Ulcer Disease PowerPoint templates (ppt) and Google Slides themes to create awesome presentations. Methods: Consecutive patients undergoing upper GI endoscopy (n = 1527) received a questionnaire consisting 23 questions related to the upper abdomen. Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. Dr. J.H. -… Log in Upload File. PEPTIC ULCER. Clipping is a handy way to collect important slides you want to go back to later. PEPTIC ULCER DISEASE (Acid – pepsin ulcer disease) G JUMBI SURGICAL ANATOMY • ANATOMY (Stomach and duodenum) -gross anatomy. Fig: Peptic ulcer disease Causes or Reasons for Peptic Ulcer Disease: The different causes for peptic ulcer are-Infection with Helicobacter pylori (H. Pylori), Use of painkillers called nonsteroidal anti-inflammatory drugs such as Ibuprofen, Aspirin, and Naproxen. Laboratory tests for H. pylori. 1. - Microscopic anatomy. Background: A prospective study was performed in order to assess the clinical presentation of peptic ulcer. Post on 13-Nov-2014. AIMST University, Malaysia. A peptic ulcer in a child looks the same as it does in an adult, and many of the aetiologies of peptic ulcer disease in children are similar to those in adults. The initial management of a stable patient with dyspepsia differs from the management of an unstable patient with upper gastrointestinal (GI) hemorrhage. Peptic Ulcer. Natural history of peptic ulcer. Ulcer occurring in either of these two sites is called peptic ulcer . Epidemiology • Peptic ulcers are common and it has been estimated that up to 10% of the population has an ulcer and annual incidence of symptomatic peptic ulcer about 0.3%. The genetics of peptic ulcer disease. Less common causes are severe physiological stress (e.g., severe illness, burns, or surgery) or hypersecretory states (e.g., Zollinger‐Ellison syndrome). At least one person in every ten is likely to have a Peptic Ulcer at one time or another. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. Fig: Peptic ulcer disease Causes or Reasons for Peptic Ulcer Disease: The different causes for peptic ulcer are-Infection with Helicobacter pylori (H. Pylori), Use of painkillers called nonsteroidal anti-inflammatory drugs such as Ibuprofen, Aspirin, and Naproxen. Peptic Ulcer Causes Two common causes of peptic ulcers include changes in the balance of stomach acid triggered by Helicobacter Pylori (H. Pylori) infection or the use of non-steriodial anti-inflammatory drugs (NSAIDs). Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. He or she may look for H. pylori using a blood, stool or breath test. Epidemiology. [1] They newly began in around 53 million people in 2014 [4] About 10% of people develop a peptic ulcer at some point in their life [5]. Ulcer may occur anywhere in the body. There are various risk factors for the development of peptic ulcer disease, but the most important ones are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs). Dr. J.H. Download Peptic Ulcer Disease PowerPoint templates (ppt) and Google Slides themes to create awesome presentations. Precautions. Chronic use of NSAIDS (aspirin, ibuprofen, naproxen) weakens and thins the mucosal lining of the stomach and duodenum and greatly contributes to the formation of breaks in the protective lining. In the latter scenario, failure of medical management not uncommonly leads to surgical intervention. Dr. S. Parasuraman Gastric ulcer formation may be related to back-diffusion of acid through damaged mucosa. A peptic ulcer is a mucosal defect in the wall of the stomach or duodenum that penetrates the muscularis mucosa. Gastric ulcer: It occurs in stomach particularly in lower half portion. Barnard ; Dept. If you continue browsing the site, you agree to the use of cookies on this website. - Blood supply. PEPTIC ULCER DISEASE Hannah Vawda FY1 * * * * * * * * * * * * * * 1 calcium antagonists, nitrates, theophyllines, bisphosphonates, steroids and NSAIDs. Types. Peptic ulcer disease (PUD) is one of the commonest diseases seen throughout the world. admission to intensive care) 5. Obtaining a medical history, especially for peptic ulcer disease, H pylori infection, ingestion of nonsteroidal anti-inflammatory drugs (NSAIDs), or smoking, is essential in making the correct diagnosis. Home; Documents; Peptic Ulcer Disease Ppt; prev. Ulcers that form in the stomach are called gastric ulcers; in the duodenum, they are called duodenal ulcers. In peptic ulcer disease, excessive secretion of hydrochloric acid diminishes the protective effects of mucus secretion and acid neutralization. Increased gastric acid secretion. Definition of peptic ulcer. Peptic ulcers (gastric and duodenal) appeared on the surgical scene (perhaps as a new disease, but more probably because they had not been diagnosed previously), and in 1881 Ludwig Rydygier cured a young woman of her gastric ulcer by removing it. presentation of perforated peptic ulcer Patients with perforated PUD usually present with an acute onset of abdominal pain. Can Diet Help? See our User Agreement and Privacy Policy. Often, they can tell you the exact timeof the perforation. Drugs: NSAI, Aspirin, cortisone and cytotoxic drugs.. Cigarette smoking. Patient Case Presentation A 61-year-old American woman was referred to a Gastroenterology Clinic from primary care provider due to consistent discomfort and significant weight loss. Barnard ; Dept. Chronic symptoms include ulcer perforation and stricture formation. Looks like you’ve clipped this slide to already. INTRODUCTION Peptic ulcer disease (PUD) is a common disorder that affects millions of individuals worldwide It is accounting for roughly 10% of medical costs for digestive diseases Higher prevalence in developing countries H. Pylori is sometimes associated with socioeconomic status and poor hygiene In the US Lifetime prevalence is ~10%. The pain starts in the epigastrium but by the time of presentation in the emergency department, it is generalized and associated with diffuse peritonitis. If you continue browsing the site, you agree to the use of cookies on this website. Title: Stomach and Duodenum Peptic Ulcer - Pathology, clinical features, management Author: Administrator Last modified by: KFH Created Date: 9/2/2002 4:01:47 PM – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 6d3260-NjAwO Refractory peptic ulcers are defined as ulcers that do not heal completely after 8 to 12 weeks of standard anti-secretory drug treatment. Peptic ulcers have characteristic symptom of dull, continuous, throbbing pain before meal time or sharp, shooting pain experienced while consuming meals … Drugs: NSAI, Aspirin, cortisone and cytotoxic drugs.. Cigarette smoking. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Dordrecht, Kluwer Academic Publishers, 1991, pp 273–282. When it occurs in stomach its gastric ulcer. Ulcers damage the mucosa of the alimentary tract, which extends through the muscularis mucosa into the sub mucosa or deeper. Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. Ulcers are deep lesions penetrating through the entire thickness of the gastrointestinal tract mucosa and muscularis mucosa. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. Complications and treatment. ; The erosion of a circumscribed area may extend as deeply as the muscle layers or through the muscle to the peritoneum. Peptic ulcers not associated with H pylori infection or the use of non-steroidal anti-inflammatory drugs are now also imposing substantial diagnostic and therapeutic challenges. 2009 Jan;33(1):80-5. doi: 10.1007/s00268-008-9796-1. They resulted in 301,000 deaths in 2013 down from 327,000 deaths in 1990 [6]. Aims: Definition of peptic ulcer. You can change your ad preferences anytime. Peptic ulcers most commonly occur in the duodenum and are more prevalent in patients between 40 – 60 years of age. But by region or area peptic ulcers are three types and are-Oesophageal Ulcer, Gastric Ulcer, Duodenal Ulcer. Increased gastric acid secretion. Other forms of peptic ulcer (non‐Hp, non‐NSAID) Risk factors for peptic ulcer. Title: Stomach and Duodenum Peptic Ulcer - Pathology, clinical features, management Author: Administrator Last modified by: KFH Created Date: 9/2/2002 4:01:47 PM – A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 6d3260-NjAwO Title: Peptic Ulcer Disease 1 Peptic Ulcer Disease . Cont’d. • Gastric ulcers occurs mostly in the lesser curvature of the stomach. Peptic Ulcer. Peptic Ulcer • An Ulcer is … Erosion in the lining of the stomach or the first part of the small intestine, an area called the duodenum. Some common types of peptic ulcer are: Duodenal ulcer: It occurs in duodenum just after the pylorus of the stomach. Types. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. out of 18. Now customize the name of a clipboard to store your clips. Pantoprazole sodium hydrate 718635-09-7-api, No public clipboards found for this slide. Perforated and bleeding peptic ulcer clinical practice guidelines were released in January 2020 by the World Society of Emergency Surgery. Read Irritable Bowel Syndrome: Psychosocial Assessment and Treatment | eBook... No public clipboards found for this slide. Ulcer :- An Ulcer is a discontinuity or break in a bodily membrane, or breach in the epithelium . the duodenum) may be called a duodenal ulcer. Home; Documents; Peptic Ulcer Disease Ppt; prev. out of 18. Peptic ulcer disease (PUD) is defined as a mucosal break larger than 3 mm in depth in the stomach or duodenum. (Uphold Graham, 2003) 3 Peptic Ulcers Gastric Dudodenal 4 PUD Demographics . Faculty of Pharmacy, The clinical presentation, diagnosis, treatment for gastric vs. duodenal ulcers are different. Etiology and pathophysiology of peptic ulcer. Clipping is a handy way to collect important slides you want to go back to later. Epidemiology of peptic ulcer. Bleeding is also the major cause of mortality in patients older than 65 years [15]. NSAIDs 3. corticosteroids 4. severe physiological stress/illness (e.g. Your doctor may recommend tests to determine whether the bacterium H. pylori is present in your body. Peptic ulcers are present in around 4% of the population. The breath test is the most accurate. Causes. As for symptomatic presentation of peptic ulcer (Figure 1), stomach pain was the most frequently recorded symptom (88.4%) followed by hyperacidity (60.6%), underweight (57.4%), vomiting (40.6%), loss of appetite (39.4%) while vomiting of blood was found to be least frequent (7.7%). Raika Jamali M.D. She looked for a PCP’s advice as she had a tarry stool in the early morning which she had never experienced before. Peptic ulcers are present in around 4% of the population. In duodenum its duodenal ulcer. It is possible to get an ulcer almost anywhere. Epidemiology. PUD affects ~4.5 million annually. of Surgery; 2 Historical Aspects. In order to detect an ulcer, your doctor may first take a medical history and perform a physical exam. Clinical Complications The acute clinical complication of ulcers is bleeding and approximately occurs in 15%-20% of . peptic ulcer disease.PPT 1. Peptic Ulcer Disease (PUD) by FreeMedsite May 21, 2020 May 21, 2020. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Gastric ulcer: It occurs in stomach particularly in lower half portion. next. Clinical presentation and diagnosis of peptic ulcer. of Surgery; 2 Historical Aspects. Despite the popular belief that peptic ulcers are caused by spicy foods or stress, the reality is that most of the time, peptic ulcers are caused by infection with a bacterium called Helicobacter pylori or use of NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen; ulcers caused by NSAIDs are associated with increased risk of complications. The initial management of a stable patient with dyspepsia differs from the management of an unstable patient with upper gastrointestinal (GI) hemorrhage. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. Treatment of peptic ulcers varies depending on the etiology and clinical presentation (see Guidelines). Peptic ulcer is one of the common GI disorders. But if the amount of acid is increased or the amount of mucus is decreased, you could develop an ulcer. It may also occur in esophagus, pyloric channel, duodenal loop, jejunum, and Meckel’s diverticulum. Post on 13-Nov-2014. If you continue browsing the site, you agree to the use of cookies on this website. A peptic ulcer in the upper part of the small intestine (i.e. Sina Hospital. Patients generally present with dyspepsia or peptic ulcer bleeding. See our Privacy Policy and User Agreement for details. The significant similarities in pathofhysiology and medical management make their discussion under one heading possible. Causes. This can be confirmed with biopsies obtained at endoscopy and urea breath test, the combination of the two resulting in a detection rate of close to 100… Location and symptoms. Most Popular; Study; Business; Design; Data & Analytics; Explore all categories; peptic ulcer disease ppt. See our User Agreement and Privacy Policy. Author: Shahab Shahid MBBS • Reviewer: Uruj Zehra MBBS, MPhil, PhD Last reviewed: August 31, 2020 Reading time: 6 minutes Peptic ulcer disease usually involves the mucosal lining of stomach or duodenum (first layer of the inner lining of the stomach or duodenum). Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)The most common causes of peptic ulcers are infection with the b… - Microscopic anatomy. You then may need to undergo diagnostic tests, such as: 1. ):80-5. doi: 10.1007/s00268-008-9796-1 sores that develop on the etiology and clinical presentation ( see guidelines ) patients present! Severe physiological stress/illness ( e.g tract mucosa and muscularis mucosa into the sub mucosa or deeper [ 15 ] NSAID! Inner surface of the gastrointestinal mucosa occurring in areas exposed to peptic ulcer ppt and pepsin and most caused! Scored on a linear scale and a symptom score was calculated ( ppt and. 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